Because Gamma Knife radiosurgery is minimally invasive, the recovery period is short and relatively mild. Most patients are able to return to normal activities, including work, within just a day or two. Some patients experience fatigue, headache and nausea for a couple of days. Your doctor can prescribe medication to help ease your symptoms, if necessary. You may also have itchiness or discomfort on your scalp where the headframe pins were attached, but this will also resolve within a day or two. While the recovery period is brief, long term side effects may still occur.